Is there an advantage to using the Z axis when designing interfaces?

Below is an example of a 2 Dimensional interface

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In a 2 Dimensional design proximity and position are the greatest indicators of importance or emphasis. Designers place more important items at the top of the screen (usually) and less important near the bottom. Likewise similar items can be grouped by rows or columns to indicate relationships.

Below is a 3 dimensional representation of the same set

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Notice how things have changed. Then most important items are lower on the screen and are give greater value using perspective and size. Proximity becomes a factor not only within columns and rows but also with distance. The Z axis also allows the user to see relationships better and to view more elements than before. 8 versus 5 rows are displayed using the same image dimensions.

Here’s a great example of 3 dimensional design

What do you think?